Linear Regression

Effect of drug treatment on cellular metabolism (targeted LC/MS metabolomics analysis)

Introduction Setup Packages Data Functions Data Exploration Missing Values Negative Controls and Compound Elimination Background Negative Mode Positive Mode Data Prep and Preliminary Analysis Cleanup Distribution Plots Negative Mode Positive Mode Principal Component Analysis Background Negative Mode Postive Mode Batch Effects and Signifiance Testing Negative Mode Surrogate variable analysis Significance Testing Positive Mode Interpretation Nucleotide Metabolism Session Info Introduction Metabolomics is one of the many “omics” scientific fields that have sprung up over the past years and can be broadly summarized as the study of the chemical composition of cells, tissues, and biofluids.